Wall and Melzack's Textbook of Pain e-Edition

The Textbook of Pain is the definitive resource for pain physicians, founded by the 'fathers' of modern pain medicine - Patrick Wall and Ronald Melzack. This 5th Edition of Wall & Melzack’s Textbook of Pain, revised under new editorial leadership, covers virtually every aspect of pain. Describing the neurophysiology, psychology, and assessment of every type of pain syndrome. With today's full range of pharmacologic, surgical, electrostimulative, physiotherapeutic, and psychological management options. The e-dition package gives you the book plus access to a website that is continuously updated for the life of the edition. All drug information is linked to Mosby's Drug Consult, all references are linked to MEDLINE/PubMed, and all illustrations and tables can be downloaded into PowerPoint® slides for presentations.

Reviews

"It goes without saying that Wall and Melzack's work is the preemptive text on pain…Required reading for all pain specialists."
— Journal of Neurosurgical Anesthesia

“An indispensable resource…A masterpiece.”
— NEJM

“The most comprehensive of any of the books dealing with pain."
— JAMA

Features

The most complete coverage of the physiology, psychology, assessment, and management of pain available
International board of contributors consisting of the leading figures in pain medicine
Latest edition ensures that this title is once again the most current, reliable, and complete core reference in the field

What's New

Features the expertise of two highly respected new editors — Stephen McMahon PhD and Martin Koltzenburg MD PhD — as well as many leading experts for a completely fresh look at the subject
Uses a new format designed to present therapeutic options in an easy-to-review manner
Provides increased coverage of anaesthetic techniques
Incorporates the most recent pharmacologic developments involving drug categories such as anticonvulsants, antidepressants, muscle relaxants, and cannabinoids
Several new chapters, including ones focusing on addiction to pain medication, clinical trials, evidence-based medicine in pain, and an extended headache section (1 chapter in the 4th edition compared to 4 chapters in this edition)
Provides a full range of new illustrations to provide a colourful and graphic representation of important concepts
Accurately reflects all of the developments that have taken place in this rapidly moving field

Contents

Section 1. Neurobiology of pain

1. Peripheral mechanisms of cutaneous nociception

2. Cellular and molecular properties of primary afferent neurons

3. Inflammatory mediators and modulators of pain

4. Neuroanatomical substrates of spinal nociception

5. Plasticity and pain: role of the dorsal horn

6. Representation of pain in the brain

7. Central nervous system mechanisms of pain modulation

8. Development of pain pathways and mechanisms

9. The genetics of pain

10. Animal models of pain

11. Ascending projection systems

12. Autonomic-endocrine-immune interactions in acute and chronic pain

13. Itch

Section 2. Assessment and psychology of pain

14. Emotions and psychobiology

15. Cognitive and learning aspects

16. Psychiatric disorders and pain

17. Studies of pain in human subjects

18. Pain assessment in adult patients

19. Measurement and assessment of paediatric pain

20. Assessment of pain beliefs, coping, and function

21. Hypnotic analgesia

22. The cognitive-behavioural approach to pain management

23. Pain, opiates and addiction

24. Placebo analgesia

Section 3. Pharmacology and Treatment of Pain

25. Central pharmacology of nociceptive transmission

26. Methods of therapeutic trials

27. Opiates: basic mechanisms

28. Opioids: clinical use

29. Antipyretic analgesics: basic aspects

30. NSAIDs and Coxibs: clinical use

31. Antidepressant analgesics: a systematic review and comparative study

32. Anticonvulsant medications in neuropathic pain

33. Local anaesthetic blocks and epidurals

34. Cannabinoids

35. Analgesic drugs in development

36. Supratentorial neurosurgery for the treatment of pain

37. Spinal cord and brain stimulation

38. Transcutaneous electrical nerve stimulation and acupuncture

39. Peripheral and central nervous system surgery for pain

40. Physiotherapy and pain

Section 4. Clinical states: Deep somatic tissue

41. Basic mechanisms of deep somatic pain

42. Postoperative pain and its management

43. Osteoarthritis and rheumatoid arthritis

44. Myofascial pain and fibromyalgia syndrome

45. Surgical treatment for back and neck pain

46. Low back pain

47. Repetitive strain injury

Section 5. Viscera

48. Visceral pain: basic mechanisms

49. Thorax

50. A clinical perspective on abdominal pain

51. Genitourinary pain

52. Obstetric pain

Section 6. Clinical States: Headache and facial pain

53. Acute and chronic dental and orofacial pain

54. Headache

55. Primary neurovasuclar headache

56. Tension-type headache

57. Pain in and around the eye

Section 7. Clinical states: Neuropathic pain

58. Response of nerves to injury in relation to neuropathic pain

59. Mechanisms of experimental neuropathic pain: integration from animal models

60. Central consequences of peripheral nerve damage

61. Phantom limb

62. Painful peripheral neuropathies

63. Trigeminal and glossopharyngeal neuralgia

64. Complex regional pain syndromes

65. Root disorders and arachnoiditis

66. Pain following spinal cord injury

67. Central pain

68. Pharmacological therapy for neuropathic pain

Section 8. Clinical states: Cancer pain

69. Cancer pain: causes, consequences and therapeutic opportunities

70. The assessment of cancer pain

71. Analgesic therapy and palliative care in children

72. Cancer pain: treatment overview

73. Pain control in the care of the dying

Section 9. Clinical States: Special cases

74. Pain in the elderly

75. Sex and gender differences in pain and its relief

76. Epidemiology of pain

Index